Target Level for LDL-Cholesterol Lowering in Coronary artery disease in Japa
Phase 4
Recruiting
- Conditions
- DL-Cholesterolemia in Stable Coronary Artery Disease
- Registration Number
- JPRN-UMIN000004938
- Lead Sponsor
- ational Hospital Organization
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 3000
Inclusion Criteria
Not provided
Exclusion Criteria
1) Acute coronary syndrome(Unstable angina,patients who had a myocardial infarction within 2 weeks) 2) abnormal liver function(AST/ALT/ALP> 3 times the upper limit of normal) 3) impaired renal function(creatinine>2 times the upper limit of normal) 4) secondary hypercholesterolemia, drug-induced hypercholesterolemia, and familial hypercholesterolemia 5) patients who cannot quit fibrates 6) Uncontrolled hypertension (systolic blood pressure over 200mmHg or diastolic blood pressure over 110mmHg) 7) Uncontrolled diabetes mellitus (HbA1c over 9.5%) 8) women who are pregnant or give the breaset, or women who have a possibility of pregnancy 9) patients judged as ineligible by doctors in charge
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Major Adverse Cardiovascular and Cerebrovascular Events (Sudden cardiac death,Lethal or Non-lethal myocardial infarction, Lethal or Non-lethal Stroke,Lethal or Non-lethal Cerebrovascular hemorrhage)
- Secondary Outcome Measures
Name Time Method 1) Death, Revascularization(Coronary arteries,Aorta,Peripheral vessels), Heart failure, Unstable angina 2) Lipid Profiles 3) Adverse events