Effects of Ramadan Fasting on Endothelial Function
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Fasting
- Sponsor
- University of Monastir
- Enrollment
- 250
- Locations
- 1
- Primary Endpoint
- Change in Reactive Hyperemia Index (RHI)
- Status
- Enrolling By Invitation
- Last Updated
- 2 years ago
Overview
Brief Summary
Include participants who intend to practice Ramadan fasting and accept to complete the three part of the study .
Detailed Description
All volunteers and stable patients that intend to fast ramadan. Each participant is examined during three separate visits. 1. The week before Ramadan (Pre-R). 2. the last week of Ramadan (R). 3. the last week of the month following Ramadan (Post-R). Participants that miss one appointement or more are exluded from the study. Patient recrutement is conducted in primary care centers of the state of Monastir, out-patients clinic (Cardiology, Endocrinology) at the emergency department of Fattouma Bourguiba university hospital after a clarified written consent. All patients benifit of an endothelial peripheral arterial tonometry (Endo-PAT) test .
Investigators
Pr. Semir Nouira
Professor
University of Monastir
Eligibility Criteria
Inclusion Criteria
- •Adult patient intending to fast Ramadan.
Exclusion Criteria
- •Age \< 18 years old
- •Hemodynamic instability.
- •Myocardial infarction requiring urgent revascularization.
- •Parkinsonism: tremor problem.
- •Refusal, communication problem.
Outcomes
Primary Outcomes
Change in Reactive Hyperemia Index (RHI)
Time Frame: the day of inclusion , 10 last day of Ramadan , 1 month after Ramadan
RHI is calculated for each participant in the day of iclusion , then it is recalculated in the two others visits.