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Effects of Ramadan Fasting on Endothelial Function

Conditions
Endothelial Dysfunction
Fasting
Registration Number
NCT05331443
Lead Sponsor
University of Monastir
Brief Summary

Include participants who intend to practice Ramadan fasting and accept to complete the three part of the study .

Detailed Description

All volunteers and stable patients that intend to fast ramadan. Each participant is examined during three separate visits.

1. The week before Ramadan (Pre-R).

2. the last week of Ramadan (R).

3. the last week of the month following Ramadan (Post-R). Participants that miss one appointement or more are exluded from the study. Patient recrutement is conducted in primary care centers of the state of Monastir, out-patients clinic (Cardiology, Endocrinology) at the emergency department of Fattouma Bourguiba university hospital after a clarified written consent.

All patients benifit of an endothelial peripheral arterial tonometry (Endo-PAT) test .

Recruitment & Eligibility

Status
ENROLLING_BY_INVITATION
Sex
All
Target Recruitment
250
Inclusion Criteria
  • Adult patient intending to fast Ramadan.
Exclusion Criteria
  • Age < 18 years old
  • Hemodynamic instability.
  • Myocardial infarction requiring urgent revascularization.
  • Parkinsonism: tremor problem.
  • Refusal, communication problem.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in Reactive Hyperemia Index (RHI)the day of inclusion , 10 last day of Ramadan , 1 month after Ramadan

RHI is calculated for each participant in the day of iclusion , then it is recalculated in the two others visits.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

University hospital Fattouma Bourguiba

🇹🇳

Monastir, Tunisia

University hospital Fattouma Bourguiba
🇹🇳Monastir, Tunisia
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