Comparison of Pressure-, Flow- and Neurally Adjusted Ventilatory Assistance (NAVA)-Triggering in Pediatric and Neonatal Ventilatory Care

Not Applicable

Completed

• Conditions: Respiration
• Interventions: Device: Triggering mode of the ventilator; Device: Triggering method of the ventilator

• Registration Number: NCT00893087
• Lead Sponsor: University of Oulu

Brief Summary

The purpose of this study is to study whether neurally adjusted ventilatory assist (NAVA) provides advantages over current methods in detecting patients own breathing efforts in pediatric and neonatal ventilatory care.

Our study hypothesis is that NAVA-technology is more accurate than currently used methods in detecting and assisting spontaneous breathing in children, and thus the patient-ventilator synchrony will improve.

Detailed Description

Asynchrony means that the timing of support given by the ventilator is different from patients own breathing pattern. Asynchrony during ventilatory care may increase the risk for complications, make the weaning more difficult and may affect the survival rates.

In this study we will compare two currently used methods pressure- and flow-triggering with a neurally adjusted ventilatory assist in synchronization of the ventilator support with patients own efforts.

Study Timeline

• Study Start: 2009-02
• Study First Submitted: 2009-05-03
• Study First Submitted QC: 2009-05-04
• Study First Posted: 2009-05-05
• Primary Completion: 2009-07
• Study Completion: 2009-08
• Status Verified: 2010-01
• Last Update Submitted: 2010-01-19
• Last Update Posted: 2010-01-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

• All children born over 30 weeks of gestation needing ventilatory care

Exclusion Criteria

• Craniofacial malformation which does not allow feeding tobe positioning. Critical ventilatory or perfusion problems.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	Triggering mode of the ventilator	Flow triggering
1	Triggering method of the ventilator	Flow triggering
2	Triggering mode of the ventilator	Pressure triggering
2	Triggering method of the ventilator	Pressure triggering
3	Triggering mode of the ventilator	NAVA triggering
3	Triggering method of the ventilator	NAVA triggering

Primary Outcome Measures

Name	Time	Method
The time in ventilator-patient synchrony in each of the assist modes.	30 min

Trial Locations

Locations (1)

University Hospital of Oulu; 🇫🇮 Oulu, Finland