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临床试验/EUCTR2011-002819-28-SE
EUCTR2011-002819-28-SE进行中(未招募)1 期

Internet-based cognitive behavior therapy in combination with D-Cycloserine for Obsessive Compulsive Disorder: A double blinded randomized controlled trial - ICBT with DCS for OCD: A double blinded randomized controlled trial

Stockholms Läns Landsting0 个研究点目标入组 128 人开始时间: 2012年1月3日最近更新:
适应症

试验速览

阶段
1 期
状态
进行中(未招募)
发起方
入组人数
128

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
All

入选标准

  • Outpatients
  • Male or female
  • = 18 years
  • Currently living in Stockholm, Uppland, Örebro, Södermanland, Gästrikland, Västmanland and Östergötland county in Sweden.
  • Primary diagnosis of OCD according to the DSM-IV-TR.
  • Signed informed consent
  • Have regular access to a computer with internet access and skills to use the web
  • Have received information about the need of using contraception
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range 120
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range 8

排除标准

  • Pregnancy or breast feeding
  • Patients unlikely to cooperate fully in the study
  • Patients not able to read or understand the basics of the ICBT self-help material
  • Psychotropic medication changes within two months prior to treatment
  • Completed CBT for OCD within last 12 months
  • Y-BOCS [21] < 16 at Psychiatrist visit (6.2.3)pi
  • OCD symptoms primarily associated with hoarding.
  • Other primary axis I diagnosis according to the Mini-International Neuropsychiatric Interview (MINI) [34]
  • Ongoing substance dependence
  • Lifetime bipolar disorder or psychosis
  • Suicidal ideation
  • Axis II diagnosis that could jeopardize treatment participation
  • Serious physical illness that will be an obstacle in ICBT and DCS
  • Other ongoing psychological treatments that could affect OCD symptoms
  • Renal impairment
  • Hypersensitivity to D-Cycloserine
  • Chronic Alcoholism

研究者

发起方
Stockholms Läns Landsting

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