3D joint space evaluation in knee osteoarthritis: The importance of weight-bearing and flexio

Recruiting

• Conditions: osteoarthritis; 10023213

• Registration Number: NL-OMON54070
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 9 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 21

Inclusion Criteria

- Patients with symptomatic knee osteoarthritis in at least one knee
- > 18 years old
- Kellgren-Lawrence grade (severity) 2 or 3
- Good knowledge of the Dutch language
- Signed informed consent

Exclusion Criteria

- Previous surgery in (both) symptomatic knee(s)
- Inability to stand for 15 minutes, without assistance
- Unable to fit knee in the MRI coil (knee width > ~15 cm)
- Not eligible for MRI, in response to the MRI safety checklist

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary study parameter is the change in median medial joint space width<br /><br>between the different positions (weight-bearing/non-weight-bearing and<br /><br>flexion/extension). </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters are:<br /><br>1. Median lateral joint space width<br /><br>2. Joint space shift size and direction<br /><br>3. Change in distance distribution</p><br>