Short-course radiotherapy with delayed surgery in unfit locally advanced rectal cancer patients.
Phase 1
Completed
- Conditions
- locally advanced rectal cancerrectal cancer,radiotherapy,short course
- Registration Number
- TCTR20150617001
- Lead Sponsor
- none
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 56
Inclusion Criteria
age over 75 years; histologically confirmed adenocarcinoma of the extraperitoneal rectum (defined as < 12 cm from distal tumour to anal verge, as measured by rigid sigmoidoscopy); no evidence of distant metastases on a chest and abdomen CT scan; active co-morbidities (defined by the co-morbidity index according to the Charlson score) (23) which made patients unfit for chemotherapy; logistical difficulties in receiving standard treatment with or without co-morbidities; patient refusal of chemotherapy.
Exclusion Criteria
ineligibility for surgery, previous pelvic RT or active pelvic inflammatory disease.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method