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A Survey of Lanadelumab in Participants with Hereditary Angioedema

Not Applicable
Recruiting
Conditions
Hereditary Angioedema
Registration Number
JPRN-jRCT2031220105
Lead Sponsor
Contact for Clinical Trial Information
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
100
Inclusion Criteria

Participants diagnosed with hereditary angioedema (HAE) and treated with Lanadelumab for the first time.

Exclusion Criteria

Not Applicable

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1.Number of Participants Who Experienced At Least One Treatment-Emergent Adverse Event (TEAE)<br>Time Frame: 12 Months<br>An adverse event (AE) is any untoward medical occurrence in a patient administered a medicinal product. An adverse event does not necessarily have a causal relationship with the intervention. An adverse event can therefore be any unfavorable and unintended sign (including an abnormal laboratory finding, for example), symptom, or disease temporally associated with the use of a medicinal product, whether or not considered related to the medicinal product.
Secondary Outcome Measures
NameTimeMethod
1.Number of Angioedema Attacks <br>Time Frame: 12 Months<br>Number of angioedema attacks during the study will be assessed.<br><br>2.Angioedema Quality of life (AE-QoL) Questionnaire<br>Time Frame: 12 Months<br>The AE-QoL questionnaire is a self-administered validated instrument to assess health related (HR)QoL among participants with recurrent angioedema (including HAE). The AE-QoL consists of 17 disease-specific quality-of-life items, to produce a total AE-QoL score and 4 domain scores (functioning, fatigue/mood, fear/shame, and nutrition) and each of the 17 items has a five-point response scale ranging from 1 (Never) to 5 (Very Often).
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