Effect of creatine supplementation associated with a program of weight training on muscle mass, strength and physical performance in elderly with reduced muscle mass
Phase 2
- Conditions
- Sarcopenia, elderly.C10.597.613.612.500M01.060.116.100
- Registration Number
- RBR-7r7t52
- Lead Sponsor
- Faculdade de Nutrição da Universidade Federal de Goiás
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Data analysis completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Have between 60 and 80 years of age; Be diagnosed with sarcopenia.
Exclusion Criteria
Be vegetarian; Take any ergogenic aid in the last 6 months prior to study initiation; Ingest any medication that can affect muscle growth or the ability to train intensely during the study (statins, muscle relaxants, anti-inflammatory); Be involved in restricting food programs; Be involved in physical training programs; Received contrast or performed radioactive procedure last year; Have any kidney disease, liver disease and heart disease.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Increase body muscle mass by dual energy x-ray absorptiometry, from the variation of at least 10% in the pre and post intervention measurements.;Strength increase assessed by 10RM test performed in bench and leg press exercises, from the variation of at least 50% in the pre and post intervention measurements.;Increased muscle mass from the observation of variation of 4.7% in the pre and post intervention measurements and superior gain when compared to placebo group.;Significant increase, on the measurements of pre and post intervention, from the variation of 78.2% and 89.7% 4.7% performed in bench press and leg press exercises.
- Secondary Outcome Measures
Name Time Method Increase bone mineral density by dual energy x-ray absorptiometry, from the variation of at least 5% in the pre and post intervention measurements.;Increase bone mineral content by dual energy x-ray absorptiometry, from the variation of at least 5% in the pre and post intervention measurements.;Bone mineral density did not change in pre and post intervention and between groups.;Bone mineral content did not change pre and post intervention and between groups.