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Clinical Trials/NCT05724394
NCT05724394
Active, not recruiting
Not Applicable

A Feasibility Randomized Controlled Trial of Culturally Adapted Getting Better Bite-by-Bite (Ca-GBBB)Intervention for Individuals With Eating Disorders in Pakistan

Pakistan Institute of Living and Learning1 site in 1 country84 target enrollmentApril 28, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Eating Disorders
Sponsor
Pakistan Institute of Living and Learning
Enrollment
84
Locations
1
Primary Endpoint
Intervention Log
Status
Active, not recruiting
Last Updated
last year

Overview

Brief Summary

This is a mixed method feasibility randomized controlled trial to explore the feasibility and acceptability of therapist delivered, culturally adapted, manualized Ca-GBBB intervention for Eating Disorders (EDs) - Bulimia Nervosa (BN) and Bing Eating Disorder (BED) in Pakistan.

Detailed Description

Evidence on psychological management of eating disorders in low and middle income countries ( LMICs) is limited, and non-existent in Pakistan. A Cognitive Behaviour Therapy (CBT) based guided self-help manual "Getting Better Bite by Bite: A Survival Kit for Sufferers of Bulimia Nervosa and Binge Eating Disorders" (GBBB), has found to be feasible and acceptable for patients with BN. Quantitative phase of this research aims to determine if the culturally adapted GBBB (Ca-GBBB) programme is feasible and acceptable for individuals with Eating disorders- BN and BED compared to treatment as usual. The qualitative part of the study will include focus groups and in-depth digitally recorded one-to-one interviews with participants by trained qualitative researchers at two time points both before and after the intervention. These focus groups and in-depth interviews will continue till the data saturation is achieved. Moreover, in-depth digitally-recorded interviews with stakeholders (nutritionists, dietitian, educationist, therapists, health professionals, etc) will also be conducted by trained researchers.

Registry
clinicaltrials.gov
Start Date
April 28, 2023
End Date
December 30, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age18 years
  • Screen positive on the Binge Eating Screening Questionnaire and/or Bulimic Investigatory test, Edinburgh
  • Residents of the study catchment area
  • Able to provide informed consent

Exclusion Criteria

  • Aged under 18
  • Presence of any severe mental or physical illness that would prevent individual from participating in the intervention and or assessments.
  • Temporary resident unlikely to be available for follow-up

Outcomes

Primary Outcomes

Intervention Log

Time Frame: During 4-month intervention period.

Feasibility of the intervention delivery: Duration of each session and completed feedback forms. This will be assessed by keeping record of whether the Ca-GBBB is delivered, received and enacted as intended.

Attendance logs

Time Frame: From baseline to 4-month follow up

Therapy logs will include each participant's attendance in a session. This will give information about acceptability of intervention. mean attendance rate of \>70% i.e. at least 11 sessions, will indicate that the intervention is acceptable for the participants

Client Satisfaction Questionnaire

Time Frame: From baseline to 4-month follow up

Tolerability of the intervention is defined as the ability to endure the intervention. Items on Client Satisfaction Questionnaire are scored on a four-point Likert scale from 1 (low satisfaction) to 4 (high satisfaction), with different descriptors for each response point. Totals range from 8 to 32; with higher scores indicating greater satisfaction.

Recruitment and attrition Logs

Time Frame: One year's time

The parameters feasibility of undertaking the trial of intervention will include the recruitment rate (the number of patients referred/approached, proportion of those who consented out of all the eligible patients with BED and/or BN disorder referred from and approached at the recruitment sites) (The success criterion of feasibility will be to recruit \> 50% of eligible participants) and the attrition rate (the number of patients withdrawn out of those who consented to participate).

Secondary Outcomes

  • Eating Disorder Examination Questionnaire(Change in score from baseline to 4-month follow-up)
  • Beck Depression Inventory(Change in score from baseline to 4-month follow-up)
  • Beck Scale for Suicidal Ideation(Change in score from baseline to 4-month follow-up)
  • The Bulimic Investigatory Test, Edinburgh(Change in score from baseline to 4-month follow-up.)
  • Kessler Psychological Distress Scale(Change in score from baseline to 4-month follow-up)
  • Binge-Eating Disorder Screener(Change in score from baseline to 4-month follow-up)
  • Oslo- 3 Social Support Scale(Change in score from baseline to 4-month follow-up)
  • Client Satisfaction Questionnaire(Change in score from baseline to 4-month follow-up)
  • The Sick, Control, One, Fat, Food(Change in score from baseline to 4-month follow-up)

Study Sites (1)

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