A Randomised Controlled Trial of Imagery Rehearsal Therapy (IRT) of Nightmares in a Psychiatric Population
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 112
- 试验地点
- 6
- 主要终点
- Frequency of nightmares scored in prospective daily nightmare logs
研究概览
简要总结
The purpose of this study is to determine whether Imagery Rehearsal Therapy(IRT) is effective in the reduction of the number of nightmares and the nightmare distress in a population of patients with psychiatric disorders.
详细描述
Within the normal population 4-8% of the people suffer regularly from nightmares. Clinical observations show that nightmares are a common problem for patients who suffer from all kinds of psychiatric disorders, and not just for the patients diagnosed with PTSD. Often nightmares can lead to sleep disorders, which have a negative impact on emotional well-being and cognitive functioning during the day. As well as this a strong relationship between severity of nightmares and severity of psychopathology has been found. This gives a strong argument for treatment of nightmares as a symptom, separate from the psychiatric disorder.
A few controlled studies of the treatment of nightmares have been published, in which behavioral therapy, relaxation techniques, exposure and systematic desensitization have been studied, all of which have shown positive results. But these techniques do not seem to reduce the number of nightmares in patients who suffer from PTSD. These last few years more controlled studies of a cognitive behavioral technique called 'Imagery Rehearsal Therapy' (IRT) have been published. With IRT patients have to change the script of their nightmares into a different outcome, and rehearse this new script using cognitive imagery a few times a day.
Comparisons: treatment of nightmares with IRT compared to a waitlist control group who do not get IRT until 6 months later.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients referred to GGZ Centraal (previously Symfora groep) by their family doctor/GP for treatment of a psychiatric disorder. Patients that suffer from anxiety disorders, eating disorders, mood disorders and/or personality disorders.
- •Inclusion Criteria:
- •Minimum of 3 nightmares per month
- •Nightmares are associated with distress in daily life
- •Subject wants to get treatment for the nightmares
排除标准
- •Imagery rehearsal therapy for nightmares in the past
- •Psychotic disorders
- •Acute psychiatric crisis
- •Mentally challenged or neuropsychiatric syndrome
- •Severe addiction problems
- •Insufficient mastery of the Dutch language
结局指标
主要结局
Frequency of nightmares scored in prospective daily nightmare logs
时间窗: Daily logs for 18 weeks, then periods of 4 weeks every 3 months
Frequency of nightmares scored on the Nightmare Frequency Questionnaire
时间窗: At beginning of trial, 4, 16, 30, 42 and 56 weeks
次要结局
- Intensity of nightmares scored in prospective daily nightmare logs(Daily logs for 18 weeks, then periods of 4 weeks every 3 months)
- Effects of nightmares scored on the Nightmare Effects Survey(1, 4, 16, 30, 42 and 56 weeks)
- Nightmare distress scored on the Nightmare Distress Questionnaire(1, 4, 16, 30, 42 and 56 weeks)
- Sleep problems scored on the SLEEP-50(1, 4, 16, 30, 42 and 56 weeks)
- Psychiatric symptoms scored on the Symptom Check List (SCL-90)(1, 4, 16, 30, 42 and 56 weeks)
- Symptoms of post-traumatic stress disorder scored on the Zelf Inventarisatie Lijst PTSS ZIL (= PTSD Inventory)(1, 4, 16, 30, 42 and 56 weeks)
- Quality of life scored on the abbreviated World Health Organization Quality of Life scale (WHOQoL-Bref)(1, 4, 16, 30, 42 and 56 weeks)
- Nightmare efficacy and content measured by Nightmare Efficacy & Content Questionnaire(1, 4, 16, 30, 42 and 56 weeks)
研究者
Annette van Schagen
Clinical psychologist
GGZ Centraal