Fractional FLOw Reserve In Cardiovascular DiseAses
- Conditions
- Coronary Artery DiseaseAcute Coronary Syndrome
- Registration Number
- NCT04597489
- Lead Sponsor
- LinkCare GmbH
- Brief Summary
The FLORIDA (Fractional FLOw Reserve In cardiovascular DiseAses) study sought to investigate outcomes of FFR-guided versus angiography-guided treatment strategies in a large, real-world cohort.
- Detailed Description
The objective of the FLORIDA study was to investigate mortality outcomes of FFR-guided versus angiography-guided treatment strategies in a large, real-world patient cohort, including patients with different stages of coronary artery disease as well as patients with acute coronary syndrome (ACS). All patients were followed for a period of 3 years after the index date. The analysis period extended from the individual index date to the date of death or the end of the 3-year follow-up period. Patients were matched for sex, presence of acute coronary syndrome, age ± 5 years, and propensity scores estimated with logistic regression based on 72 variables , with each FFR patient matched to the closest angiography-only patient
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 64045
- At least one inpatient coronary angiography for suspected coronary artery disease between January 2014 and December 2015.
- Loss to follow-up of other reasons than death (i.e. change of insurance)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method All-cause mortality 36 months All patients were followed for a period of 3 years after the index date. The analysis period extended from the individual index date to the date of death or the end of the 3-year follow-up period. The primary endpoint was mortality at 3 years, prospectively assessed at a quarterly basis.
- Secondary Outcome Measures
Name Time Method All-cause mortality 24 months Prospectively assessed at a quarterly basis.
Trial Locations
- Locations (1)
LinkCare GmbH
🇩🇪Stuttgart, Germany
LinkCare GmbH🇩🇪Stuttgart, Germany