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临床试验/NCT04217538
NCT04217538已完成不适用

Observational Study of a Cohort of Patients With Hereditary Epidermolysis Bullosa That Come for Their Annual/Biannual Check up at This Medical Rare Disease Reference Centers (MRDRC) of This Disease in France and Belgium

Centre Hospitalier Universitaire de Nice2 个研究点 分布在 1 个国家目标入组 41 人开始时间: 2017年1月4日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
41
试验地点
2
主要终点
Dental structural abnormalities and/or caries

研究概览

简要总结

Hereditary Epidermolysis Bullosa (EBH) are rare dermatologic diseases characterized by cutaneous and mucosa fragility. Oral manifestations of few small cohort have been published. The main objective of this multicentric cohort study first in Europe was to report the oral status of these patients that were consulted in the MRDRC of this disease in Nice (France), Toulouse (France) and Louvain (Belgium). Then a correlation between the oral characteristics and the EBH type will be made, in order to facilitate the management of patient care and the prevention program that can be established to improve their oral health.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
7 Months 至 78 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patient with EBH
  • patient consent for examination and use the clinical data for publication purpose

排除标准

  • 未提供

结局指标

主要结局

Dental structural abnormalities and/or caries

时间窗: 1 day

number of defect /dental caries dor each toth

次要结局

  • oral lesion(1 day)
  • gingival biotype(1 day)
  • gingival status(1 day)
  • plaque and gingival index(1 day)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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