A placebo controlled study on the effect of oxandrolone in combination with authentic biosynthetic human growth hormone and low-dose oestrogens on growth and metabolic parameters in girls with Turner's syndrome.
Completed
- Conditions
- girls with Turner syndrome
- Registration Number
- NL-OMON23518
- Lead Sponsor
- Pfizer (New York), previously Pharmacia; and Lilly (Indianapolis, USA)
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 135
Inclusion Criteria
Turner syndrome, confirmed by chromosomal analysis. 3 age ranges: 2.00-7.99 yrs, 8-11.99 yrs, 12.00-15.99 yrs.
Exclusion Criteria
1. Any other disorder that may affect growth;
2. Hydrocephalus;
3. Other experimental drug study;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Final height.
- Secondary Outcome Measures
Name Time Method Potential side effects (glucose intolerance; lowering of the voice); <br />psychosexual changes.