The determinants of corneal curvature in healthy participants and in cataract surgery patients
Not Applicable
Active, not recruiting
- Conditions
- Cornea after Cataract surgeryEye - Diseases / disorders of the eye
- Registration Number
- ACTRN12616001593426
- Lead Sponsor
- The University of Auckland
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 180
Inclusion Criteria
Part 1 and 2: Ametropia <1D (defocus or astigmatism). Participants can be healthy volunteers.
Part 3:Patients scheduled for routine cataract surgery.
Exclusion Criteria
Part 1: Ametropia >1D (defocus or astigmatism)
Part 1, 2 and 3:Pre-existing ocular pathology or previous ocular surgery, Contact lens use,
Strabismus, Previous ocular trauma
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Relationship between biomechanics of the cornea, using Corvis-ST, and surgically induced astigmatism, using tomographer (Galilei 2), following cataract surgery.<br><br>[Patients will be assessed at least a few hours before surgery, and, one day, one month and three months after the surgery. ];Relationship between biomechanics of the cornea and wound architecture following cataract surgery. Biomechanics of the cornea will be measured by Corvis-ST and wound architecture by anterior segment optical coherence tomographer (AS-OCT) and Specular microscopy.<br><br>[Patients will be assessed at least a few hours before surgery, and, one day, one month and three months after surgery.]
- Secondary Outcome Measures
Name Time Method Topographical maps and corneal higher order aberrations obtained by 4 different aberrometers (Zywave, OPDIII, iTrace and Galilei 2) will be compared. This is a composite secondary outcome.[This is the first part of the study. Three months from the commencement of the project. ]