The Cognitive and spOrt Virtual EPIC Training Study for Cardiovascular Diseases
- Conditions
- Cardiovascular Diseases
- Interventions
- Behavioral: Physical exercise trainingBehavioral: Cognitive training
- Registration Number
- NCT04661189
- Lead Sponsor
- Montreal Heart Institute
- Brief Summary
COVEPICARDIO trial is designed to document the effects of remote monitoring of physical exercise and home-based cognitive training on cognitive and physical functions in older adults with cardiovascular diseases.
- Detailed Description
Cardiac rehabilitation is a class I level A recommendation with clinical benefits that are now well documented. Due to the COVID-19 pandemic, accessibility to rehabilitation services and exercise training programs are limited. Quarantine measures can induce collateral damages to cardiovascular and psychological health, in particular in clinical population. Cardiovascular diseases (CVD) are associated with cognitive deficits and increased risk of dementia later in life. Specifically for CVD, physical inactivity and excessive sedentary lifestyle induced by confinement decrease cardiorespiratory capacity, increase the risk of acute events and rehospitalization. Maintaining a minimum of physical activity during a health crisis is fundamental. In this context, our team has developed an innovative program of exercise and cognitive training at home. Considering the added benefits of combining cognitive training to physical exercise to further enhance health and cognition in seniors with CVD, this project also addresses the added benefits of a multidomain intervention combining a home-based physical exercise intervention with a cognitive training.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 122
- Adults aged 50 and older
- Have access to internet
- Have access to a tablet (i.e., iPad or Android) or a computer
- Diagnostic of cardiovascular disease (stable chronic systolic or diastolic heart failure, atrial fibrillation, documented atherosclerotic disease).
- Able to do light to moderate aerobic exercice training
- With no contraindication to exercise training
- Non-cardiopulmonary limitation to exercise (e.g., arthritis)
- Severe exercise intolerance
- Respiratory disease (e.g., asthma, COPD, COVID-19)
- Mini Mental Scale Examination (MMSE) telephone version lower than 19/23
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Multidomain intervention Cognitive training The multidomain intervention will combine a remote monitoring of home-based cognitive training with physical exercise training for 6-month. Physical exercise intervention Physical exercise training The physical exercises intervention will include the remote monitoring of physical exercise training for 6-month. Multidomain intervention Physical exercise training The multidomain intervention will combine a remote monitoring of home-based cognitive training with physical exercise training for 6-month.
- Primary Outcome Measures
Name Time Method Change in general cognitive functioning Baseline and post-intervention at 6 months Validated remote version of Montreal Cognitive Assessment
Change in executive functions Baseline and post-intervention at 6 months. Validated remote version of Rey auditory verbal learning test, Trail Making Test, as well as Phonological and Semantic Fluency, Similarity, and Digit Span neuropsychological tests and iPad tests (Composite Z-score).
Change in processing speed Baseline and post-intervention at 6 months Validated remote version of Rey auditory verbal learning test, Trail Making Test, as well as Phonological and Semantic Fluency, Similarity, and Digit Span neuropsychological tests and iPad tests (Composite Z-score).
Change in episodic memory Baseline and post-intervention at 6 months Validated remote version of Rey auditory verbal learning test, Trail Making Test, as well as Phonological and Semantic Fluency, Similarity, and Digit Span neuropsychological tests and iPad tests (Composite Z-score).
- Secondary Outcome Measures
Name Time Method Change in Balance performance Baseline and post-intervention at 6 months Timed one-leg standing test (s)
Change in Lower limb muscles strength Baseline and post-intervention at 6 months Timed Sit-to-Stand test (s).
Change in Walking speed Baseline and post-intervention at 6 months. 4-meter walking test (m/s).
Change in Functional mobility Baseline and post-intervention at 6 months Timed up and Go test (s).
Change in Cardiorespiratory fitness Baseline and post-intervention at 6 months Matthews cardiorespiratory fitness questionnaire (the score is an estimation of individual VO2 max (ml.kg.min) and range from 15-50, with a higher score indicating a higher VO2max)
Trial Locations
- Locations (1)
Preventive medicine and physical activity centre (centre EPIC), Montreal Heart Institute
🇨🇦Montréal, Quebec, Canada