Multicenter observational studies for lipoid congenital adrenal hyperplasia in Japa

Not Applicable

• Conditions: ipoid congenital adrenal hyperplasia

• Registration Number: JPRN-UMIN000050445
• Lead Sponsor: Keio University School of Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-04-01
• Last Update Posted: 17 October 2023
• Study Completion: 2028-03-31

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Not provided

Exclusion Criteria

The study dose not enroll patients who have other disorders causing obesity, hypertension, impaired glucose tolerance, diabetes mellitus, osteoporosis, or hypogonadism or those whom their physicians or principal investigator decide inappropriate for this study.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1) Incidence (or prevalence), onset ages, and risk factors of commodities for glucocorticoid replacement therapy Commodities such as obesity, hypertension, impaired glucose tolerance, diabetes mellitus, or osteoporosis were assessed. 2) Incidence (or prevalence), onset ages, and risk factors of commodities for ovarian function and other anatomical abnormalities Secondary sexual characteristics, premature ovarian failure, and ovarian hypertrophy, cyst, or torsion in 46,XX female cases were assessed. 3) Incidence (or prevalence), onset ages, and risk factors of commodities for testicular function Secondary sexual characteristics and spermatogenesis in 46,XY male cases were assessed.

Secondary Outcome Measures

Name	Time	Method
1) Protective or risk factors for health-related quality of life (QOL) Scores of SF36 health survey v2 (Japanese version) were assessed with other factors including age, STAR genotype, sex of raring, and amount or type of glucocorticoid or sex steroids for replacement therapy.