Patient perception and clinical effectiveness of an allogeneic cortical sheet versus an autologous laminated bone graft for the treatment of horizontal bone defects: a randomized multicenter clinical trial

ThinkingPerio Research - Periocentrum Bilbao0 sites15 target enrollmentJanuary 28, 2021

Overview

No summary available.

Registry

who.int

Start Date

January 28, 2021

End Date

September 1, 2023

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Sponsor

ThinkingPerio Research - Periocentrum Bilbao

•1\. Informed consent after detailed information
•2\. Adults at least 18 years of age
•3\. Candidates to receive a bone augmentation for implant placement
•4\. Presence of a bone defect (\=2 teeth) with at least 2 mm of mucosa
•5\. Keratinized remnant whose bone width is insufficient (\<4 mm) measured on a CBCT\-type scanner
•6\. The patient must be periodontally treated at least 1 month before the surgical intervention and in addition to all those oral factors that may affect the treatment

•1\. General contraindications for dental/surgical treatment
•2\. Inflammatory or autoimmune disease of the oral cavity
•3\. Smokers of more than 10 cigarettes a day
•4\. Allergy to collagen and analgesics/anti\-inflammatory NSAIDs
•5\. History of cancer in different parts of the body that has required radiotherapy or chemotherapy in the last 5 years
•6\. Radiation therapy to the head or neck in the last 5 years
•7\. Current medication with immunosuppressants, bisphosphonates or high doses of corticosteroids
•8\. Pregnant or nursing women
•9\. Women of childbearing age who are not using an effective contraceptive method
•10\. Participating in other biomedical research studies in the 24 weeks prior to the start of the study