Observational Study of Preoperative Screen for Substance Abuse

Completed

• Conditions: Preoperative Screen for Substance Abuse in in Patients Undergoing Emergency Operation
• Interventions: Drug: Substance use

• Registration Number: NCT02621411
• Lead Sponsor: West China Hospital

Brief Summary

Substance abuse is a growing problem world wide, and treatment of substance abusers in the perioperative period, especially for emergency operation is challenging. The objectives of this study are to determine the proportions of substance abusers in the trauma patients undergoing emergency operation by preoperative screen, observe the differences of consumption of anesthetics and other medications during perioperative period between substance abusers and non-abusers, as well as postoperative complications, and explore an optimal scheme for substance abusers.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-11
• Study First Submitted: 2015-12-01
• Study First Submitted QC: 2015-12-01
• Study First Posted: 2015-12-03
• Primary Completion: 2016-12
• Study Completion: 2017-03
• Status Verified: 2017-04
• Last Update Submitted: 2017-04-01
• Last Update Posted: 2017-04-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1031

Inclusion Criteria

• Patients aged 16~70 years；
• Informed consent signed

Exclusion Criteria

• Aged<16 years or >70 years；
• Refuse to sign consent;
• Other conditions that may preclude the patients from the study, such as language barrier, psychiatric disorders, unable to attend research center for follow up.
• Patients who enrolled to another research study or are taking experimental medication in last 3 months prior to this study.
• Not suitable for the study, after assessment by the investigators.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Substance abuser group	Substance use	After preoperative screen by application of ICG test cassette, this group of patients are found current use of the certain substance(s).

Primary Outcome Measures

Name	Time	Method
Proportion of substance abuser in all the emergency operation patients	1 year	The proportion will be calculated as the number of substance abusers / total number of enrolled calculated as the number of substance abusers / total number of enrolled patients

Secondary Outcome Measures

Name	Time	Method
Incidence and severity of postoperative complications	30 days
Perioperative consumption of medications	1 day	Perioperative consumption of sulfentanil, midazolam, propofol, and muscle relaxant in substance abusers and non-abusers.

Trial Locations

Locations (1)

West China Hospital, Sichuan University; 🇨🇳 Chengdu, Sichuan, China