Investigation of the Effect of Proximal and Distal Adductor Canal Block in Knee Replacement Surgery

Not Applicable

Recruiting

• Conditions: Knee Osteoarthritis

• Registration Number: NCT06188806
• Lead Sponsor: Umraniye Education and Research Hospital

Brief Summary

to investigate the effect of adductor canal block applied with two different approaches in the treatment of pain after TKA surgery on pain control and functional mobility.

Detailed Description

This prospective randomized trial is randomly divided into 3 groups using the method. Total knee arthroplasty is performed by the same surgical team.

is applied. The patients were divided into proximal ACB applied, distal ACB applied and control groups.

Study Timeline

• Study Start: 2023-11-10
• Study First Submitted: 2023-12-18
• Study First Submitted QC: 2023-12-18
• Study First Posted: 2024-01-03
• Status Verified: 2025-06
• Last Update Submitted: 2025-06-29
• Primary Completion: 2025-06-30
• Last Update Posted: 2025-07-01
• Study Completion: 2025-07-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 78

Inclusion Criteria

• Medications for unilateral TKA surgery

  • Patients aged 18-85
  • ASA 1-3

Exclusion Criteria

• Patients under 18 years of age and over 85 years of age

• Patients with ASA 4 and above

• Patients with cognitive impairment

• Patients with application site infection

• Patients allergic to local anesthesia

• Patients receiving anticoagulant therapy

• Patients with bleeding diathesis

• Patients with chronic opioid or substance use

• Patients with insulin-dependent diabetes mellitus

• patients with neuropathy

  • patients with hepatic or renal failure

• Patients who do not accept the procedure to be applied

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
VISUAL ANALOGUE SCALE(VAS)	POSTOPERATIVE 6, 12 AND 24 HOURS	VAS pain score was evaluated as "no pain" (score=0) and "worst pain" (score=10) and was divided into 3 groups according to the World Health Organization's pain intensity scale: score \<3 mild pain, 3-6 mild-moderate. degree pain and \>6 moderate-severe pain.

Secondary Outcome Measures

Name	Time	Method
first mobilization time	within postoperative 24 hours	The first postoperative mobilization hours of the patients will be recorded.
length of hospital stay	ONE WEEK	The time between patients' admission and discharge will be recorded.
opioid use	within postoperative 24 hours	Intravenous PCA will be applied to each patient and the total tramadol dose spent will be calculated.intravenous PCA (patient controlled analgesia) tramadol 50 mg at 10 mg / hour basal rate after loading (20 mg bolus dose + 30 minutes lock time)

Trial Locations

Locations (1)

Umraniye Education and Research Hospital; 🇹🇷 Istanbul, Umraniye, Turkey