NCT04245891已完成不适用
Neonatal Evaluation of Norepinephrine Infusion in Spinal Anesthesia for Cesarean Section
Centre Hospitalier Universitaire de Nīmes1 个研究点 分布在 1 个国家目标入组 265 人开始时间: 2016年5月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 265
- 试验地点
- 1
- 主要终点
- lactate level
研究概览
简要总结
This retrospective study aims to evaluate the fate of children born by cesarean section under spinal anesthesia with or without norepinephrine as vasopressor support for anesthesia. The main objective is to compare the initial Apgar score. The records of patients who received norepinephrine are compared to those without norepinephrine. To limit the biases of this type of study, the investigators will apply a propensity score that will include as a variable: age, ASA score, comorbidity, urgency. The patients analysed correspond to the period 2016-2017.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •age > 18
- •Spinal Anesthesia for Cesarean Section
排除标准
- •sub epidural cesarean section
- •contraindication to spinal anesthesia (allergy, severe heart disease, coagulopathy)
结局指标
主要结局
lactate level
时间窗: Just after the birth of the newborn baby
The primary endpoint is the Umbilical Cord Lactate levels
次要结局
- Umbilical Cord venous PH(Just after the birth)
- maternal arterial tension during cesarean section(0, 5,10,15, 20 25, 30,35,40 minutes after spinal anesthesia)
- incidences of mother nausea and vomiting(from beginning to cesarean section end)
- use of vasopressors(from beginning to cesarean section end)
- APGAR Score(1, 5 and 10 minutes after birth)
- Umbilical Cord arterial PH(Just after the birth)
研究者
研究点 (1)
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