Neonatal Evaluation of Norepinephrine Infusion in Spinal Anesthesia for Cesarean Section
- Conditions
- Caesarean Section;Stillbirth
- Registration Number
- NCT04245891
- Lead Sponsor
- Centre Hospitalier Universitaire de Nīmes
- Brief Summary
This retrospective study aims to evaluate the fate of children born by cesarean section under spinal anesthesia with or without norepinephrine as vasopressor support for anesthesia. The main objective is to compare the initial Apgar score. The records of patients who received norepinephrine are compared to those without norepinephrine. To limit the biases of this type of study, the investigators will apply a propensity score that will include as a variable: age, ASA score, comorbidity, urgency. The patients analysed correspond to the period 2016-2017.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 265
- age > 18
- Spinal Anesthesia for Cesarean Section
- sub epidural cesarean section
- contraindication to spinal anesthesia (allergy, severe heart disease, coagulopathy)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method lactate level Just after the birth of the newborn baby The primary endpoint is the Umbilical Cord Lactate levels
- Secondary Outcome Measures
Name Time Method Umbilical Cord venous PH Just after the birth Umbilical Cord venous PH
maternal arterial tension during cesarean section 0, 5,10,15, 20 25, 30,35,40 minutes after spinal anesthesia maternal arterial tension during cesarean section
incidences of mother nausea and vomiting from beginning to cesarean section end incidences of mother nausea and vomiting
use of vasopressors from beginning to cesarean section end use of vasopressors
APGAR Score 1, 5 and 10 minutes after birth APGAR Score
Umbilical Cord arterial PH Just after the birth Umbilical Cord arterial PH