Effect of the test food on skin viscoelasticity
- Conditions
- Healthy subject
- Registration Number
- JPRN-UMIN000051832
- Lead Sponsor
- DRC Co., Ltd.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 36
Not provided
1. Subjects who have urticaria, inflammation, eczema, trauma, acne, pimples, warts, blemishes, etc. or their traces on the evaluation site 2. Subjects with a history or current history of atopic dermatitis, or with atopic predisposition 3. Subjects who have received cosmetic treatment at the evaluation site or plan to receive it during the study period 4. Subjects who use creams, gels, all-in-one products, beauty devices, or packs on the evaluation site 5. Subjects who continuously use drugs, health foods, supplements, skin care products, cosmetics, quasi-drugs that advocate or emphasize efficacy related to the efficacy examined in this study 6. Subjects who have performed the following within the past 4 weeks or plan to do so during the study period a) Changed or started health foods, basic cosmetics or sunscreen agents used on the evaluation sites b) Exposed to ultraviolet rays beyond daily life c) Participated in other human trials d) Received a special skin care treatment on the evaluation site 7. Subjects who work night shifts or day and night shifts 8. Subjects who are undergoing treatment at medical institutions for the treatment or prevention of disease, or those who are judged to require treatment 9. Subjects with a history of serious diseases of sugar metabolism, lipid metabolism, liver function, renal function, heart, circulatory system, respiratory system, endocrine system, immune system, nervous system, psychiatric disease, alcohol or drug dependence. 10. Subjects who are at risk of developing food allergies 11. Subjects who have a smoking habit 12. Subjects who are likely to develop seasonal allergic symptoms such as hay fever and may use pharmaceuticals 13. Subjects who are pregnant, breastfeeding, or wish to become pregnant during the study period 14. Subjects who are judged by the principal investigator to be unsuitable for study participation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Skin viscoelasticity by Cutometer
- Secondary Outcome Measures
Name Time Method (1) Stratum corneum water content by Corneometer (2) Dermal thickness by DermaLab (3) Wrinkle grade on the outer corner of the eyes by visual and photographic evaluation (4) Wrinkle area percentage, total average depth of wrinkles, average depth of maximum wrinkles, and maximum depth of maximum wrinkles on the corner of the eyes using replica (5) Blemishes, wrinkles, pores, color irregularities, porphyrins, hidden spots, melanin index, hemoglobin index by VISIA imaging (6) TEWL by VAPOSCAN (7) IL-1RA/IL-1 alpha, cell area, degree of multiple exfoliation, carbonylated proteins, and Involucrin/Nile red stain using tape-stripped stratum corneum (8) Questionnaire