Implant Insertion in Defective Anterior Maxillary Ridge Augmented Using Mineralized Plasmatic Matrix Versus Autogenous Bone Graft
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Cairo University
- Enrollment
- 20
- Primary Endpoint
- Patient Satisfaction regarding esthetic results , outcome will be measure using questionnaire.
Study Overview
Brief Summary
Using growth factors obtained from patient's venous blood mixed with particulate autogenous bone the study compares bone gain by implant with gold standards.
Detailed Description
To study the effectiveness of MPM in ridge augmentation with implant insertion compared with autogenous bone graft.
-PICO-
Population (P): Patients with defective maxillary alveolar ridge requiring implant insertion.
Intervention (I): Ridge augmentation with MPM.
Comparator (C): Autogenous bone graft.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 40 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Medically free patients.
- •Evaluated bone height on CBCT to be (0-4 mm buccal bone dehiscence) and width (not less than 4.5 mm)
- •Patients with Anterior maxillary defective partially edentulous ridge.
- •Age between 18 and 40 years.
- •Both sexes.
- •Patients physically able to tolerate surgical and restorative procedures.
- •Patients with an opposing tooth to the pre-implant site.
- •Good oral hygiene.
- •Highly motivated patients.
Exclusion Criteria
- •Patients allergic to local anesthetic agent.
- •Pregnant or lactating females.
- •Presence of any pathosis in the pre-implant site.
- •Presence of any mucosal disease.
- •Presence of parafunctional habits.
- •History of oral radiotherapy.
- •History of prolonged steroids use.
- •Psychological disorders.
Arms & Interventions
Autogenous bone graft (Gold Standard).
Patients with defective maxillary alveolar ridges requiring implant insertion will have Autogenous bone graft (Gold standard) and collagen membrane to be used for bone augmentation around exposed threads of inserted dental implants.
Intervention: Autogenous bone graft (gold standard). (Other)
MPM Augmentation.
Mineralized plasmatic matrix (MPM) to be used without collagen membrane to augment the defect in the maxillary bone and cover the exposed threads of the dental implants.
Intervention: Mineralized plasmatic matrix (MPM). (Other)
Outcomes
Primary Outcomes
Patient Satisfaction regarding esthetic results , outcome will be measure using questionnaire.
Time Frame: 5 months
Secondary Outcomes
- Stability of dental implants , this will be measured using Ostell device in ISQ units.(5 months.)
Investigators
Mahmoud Usama Mahmoud El Masry
Dentist at menistry of health
Cairo University