MicroRNA as biomarker for acute stroke

Recruiting

• Conditions: 10007963; cerebral hemorrhage; cerebral infarction; stroke

• Registration Number: NL-OMON55785
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 430

Inclusion Criteria

1) Patients considered potentially eligible by EMS personnel for IVT/IAT for
whom a pre-
stroke alarm is initiated.
2) For patients included in the IS group: a National Institutes of Health
Stroke Scale >=4 or eligible for reperfusion treatment
3) Age >=18 years
4) For patients included in the IS or HS group: clinical admission on the
neurology ward

Exclusion Criteria

- Use of therapeutic heparin within 24 hours before onset of symptoms
- Extracranial malignancy (patients can be included if they have a prior
history of malignancy if the patient received curative treatment)
- Alteplase treatment started

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>In-between differences in microRNA profiles on admission to the emergency<br /><br>department and within differences in each group in time. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>clinical characteristics and radiological outcomes of the patients (all<br /><br>gathered in routine clinical practice)</p><br>