The Effect of Homemade Herbal Mouthwash Versus Chlorhexidine on Plaque Accumulation in Gingivitis. A Randomized Clinical Trial.
Overview
- Phase
- Phase 3
- Status
- Not yet recruiting
- Sponsor
- Cairo University
- Enrollment
- 12
- Primary Endpoint
- plaque index (O'Leary et al., 1972)
Overview
Brief Summary
Gingivitis is a very common oral disease that may progress to the more destructive periodontitis if not treated. As oral plaque is a key player in gingivitis, plaque control by professional scaling and oral hygiene measures represents the main line of treatment.
Among the oral hygiene measures, using chlorhexidine mouthwash is considered the gold standard in mouthwashes. However, due to its side effects, a safer and more acceptable mouthwash is needed. Therefore, this study proposes mouthwashes made of infusion of natural herbs as an alternative.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 20 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Plaque-induced gingivitis.
Exclusion Criteria
- •Medically compromised.
- •History of medications.
- •Pregnant females.
- •Periapical involvement in teeth.
- •History of periodontal surgery.
- •If gingivitis was due to local factor.
Arms & Interventions
Chlorhexidine mouthwash
Intervention: Chlorhexidine 0,12% (Drug)
Herbal Homemade Mouthwash
Intervention: herbal Mouthwash (Drug)
Outcomes
Primary Outcomes
plaque index (O'Leary et al., 1972)
Time Frame: 7 days
Plaque accumulation is tested on teeth with a probe. Number of sites having plaque accumulation will be divided by the total number of dental sites to get percentage of plaque accumulation.
Secondary Outcomes
- Bleeding on probing(7 days)
- Changes in clinical signs of inflammation (Armitage, 2004)(7 days)
- Bleeding on brushing(7 days)
- Patient's acceptance of the mouthwash(7 days)
Investigators
Ayat Gamal-AbdelNaser
PI
Cairo University