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Clinical Trials/EUCTR2010-024485-21-IT
EUCTR2010-024485-21-ITActive, not recruitingPhase 1

Dipyridamole versus Adenosine infusion in the physiologic assessment of Intermediate coronary Stenoses in the cardiac catheterization laboratorY - DAISY

FONDAZIONE TOSCANA GABRIELE MONASTERIO0 sites75 target enrollmentStarted: January 15, 2013Last updated:
Conditions
Drugs

Trial Snapshot

Phase
Phase 1
Status
Active, not recruiting
Enrollment
75

Study Overview

Brief Summary

No summary available.

Study Design

Study Type
Interventional clinical trial of medicinal product

Eligibility Criteria

Sex
All

Inclusion Criteria

  • Patients of any race, male or female gender, with a single = 50% e <75% coronary stenosis (visually extimated) at angiography, in one ore more coronary vessels. Age = 18 years. Patients should sign an informed consent prior to the enrollment in the study.
  • Are the trial subjects under 18? no
  • Number of subjects for this age range: 0
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range 25
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range 50

Exclusion Criteria

  • Known intolerance of adenosine and/or dypiridamol and/or teophylline or of the eccipients. Patients who have taken caffein or food or beverages containig caffein and/or similar substances 24 hours before the procedure. Left main or aorto-ostial lesions. Lesions in severely tortuous or calcific vessels. Severely impaired left ventricular function (EF<35%). Chronic obstructive bronchopneumopathy or bronchial asthma Atrio-ventricular block >I°. Stenosis >70% of supra-aortic vessels. Concomitant treatment with teophylline-derivatives. Concomitant therapy with phosphodiesterase inhibitors derivatives. Hypotension (PASys <100 mmHg). Atrial fibrillation. Pregnant or lactating women. Pazients with a lesion in a culprit coronary vessel in patients with prior or recent myocardial infarction. Pazients with ST-elevation myocardial infarction =5 days (lesion in non-culprit vessel).

Investigators

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