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Clinical Trials/NCT03712657
NCT03712657
Completed
Not Applicable

Multi-center Research Manual for the Perioperative Application of Enhanced Recovery After Surgery in Pediatric Acute Appendicitis

Feng Jiexiong1 site in 1 country893 target enrollmentJanuary 10, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pediatric Disorder
Sponsor
Feng Jiexiong
Enrollment
893
Locations
1
Primary Endpoint
length of stay
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

This multicenter, prospective randomized controlled study is designed to applicate perioperative Enhanced recovery after surgery (ERAS) management for children with acute complicated appendicitis, the aim is to promote postoperative recovery, shorten the hospital length of stay, and reduce the incidence of postoperative complications.

Detailed Description

The purpose of this study is through multi-center prospective RCT research, to discuss the application of ERAS in children with acute complicated appendicitis, including its preoperative rehydration, postoperative analgesia, preoperative and postoperative antibiotics application, as well as the discharge standards and so on. The major outcome is whether it can reduce the length of stay in hospital (LOS), secondary outcomes are included the incidence of postoperative complications and postoperative readmission rate, etc.

Registry
clinicaltrials.gov
Start Date
January 10, 2022
End Date
October 31, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Feng Jiexiong
Responsible Party
Sponsor Investigator
Principal Investigator

Feng Jiexiong

professor

Tongji Hospital

Eligibility Criteria

Inclusion Criteria

  • ages\<14; no gender limitation;
  • Alvarado scores ≥7;
  • preoperative radiography examination indicated complicated appendicitis;
  • Patients or their legal representatives have signed "informed consent"

Exclusion Criteria

  • complicated life-threatening disease;
  • perioperative exploration not appendicitis;
  • Recently participated in other clinical trials within 3 months;
  • Researchers found not fit to participate in this trial for any condition

Outcomes

Primary Outcomes

length of stay

Time Frame: through study completion, an average of 7 days

less hospital length of stay

Secondary Outcomes

  • first time for postoperative feeding(up to 72 hours)
  • rate of re-operation(1 months)
  • first time for postoperative exercising(1-2 days)
  • rate of postoperative complication(1 months)
  • rate of re-admission(1 months)

Study Sites (1)

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