EUCTR2012-002406-46-AT进行中（未招募）不适用
Epidermal Nerve Fibre Density Reduction as a Function of Application Time of topical high-dose and low-dose Capsaicin - Capsaicin dose and reduction of ENF density
Medizinische Universität Wien, Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin und Schmerztherapie0 个研究点开始时间: 2012年9月7日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •healthy volunteers
- •18 > age < 80
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 12
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 12
排除标准
- •anamnestic injury or surgery of the thighs
- •Nerved damage (Nervus femoralis or lumbal nerval roots 2-4)
- •lack or different information by testing of sensitivity disturbance, impaired experience of pain and temperature in the area of the fore side of the thighs
- •prior use of Qutenza or other topical capsaicin preparations in the area of the firesides of the thighs in between 3 months prior to the start of the investigation
- •known hypersensitivity to capsaicin
- •known hypersensitivity to local anesthetic ointment Emla- Creme® (Lidocaine, Prilocaine, Macrogolglycerolhydroxystearat, Carbomer)
- •known hypersensitivity to Ultrasicc® (Petrolatum, Cera Microcristallina, Stearylalkohol, Macrogolstearat 2000, Polyacrylacid, Natriumedetat, Propyl-4-hydroxybenzoat) as carrier substance of the Capsaicin 0,05% Creme
- •known hypersensitivity to Qutenza cleansing gel (Macrogol 300, Carbomer 1382, Natriumedetat, Butylhydroxyanisol)
- •known hypersensitivity to paracetamol
- •unstable hypertension, current cardiovascular event, methaemoglobinaemia, G6PDH-Insufficiency, hepatic insufficiency, use if antiarrhythmics, known alcohol or drug abuse
- •participation in another trial
- •Pregnancy or breast feeding
研究者
相似试验
已完成
4 期
Epidermal Nerve Fibre Density Reduction as a Function of Application Time of topical high-dose and low-dose CapsaiciHealthy volunteersDRKS00004587niversitätsklinik Wien12
已完成
不适用
Normative Data of Intra-epidermal Nerve Fiber DensityHealthyNCT01498211University Hospital, Strasbourg, France300
已完成
1 期
The Effect of Ablation of Epidermal Nerve Fibers Using Capsaicin CreamPainNCT01883102Mayo Clinic1
撤回
不适用
Differential Characteristics of Neuropathy in Type 2 Diabetics With and Without Lower Extremity WoundsType 2 DiabetesDiabetic NeuropathyDiabetic Foot UlcerNCT02347709Winthrop University Hospital
招募中
不适用
Change in retinal nerve fiber layer thickness after optic disc hemorrhage in non glaucomatous patientsOptic disc hemorrhage in patients with glaucoma requires intensive lower targer intraocular pressure(IOP)Optic disc hemorrhageRetinal nerve fiber layer thicknessGlaucoma progressionTCTR20210201007one13