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Perception of Objects and Natural Scenes in People With Vision Loss (ACTIVIS)

Completed
Conditions
Vision Loss
Interventions
Other: vision tests
Registration Number
NCT02862405
Lead Sponsor
Lille Catholic University
Brief Summary

The loss of central vision causes difficulty not only in reading but also in faces recognition, and in particular in the identification of facial expression, objects or spaces. These visual deficits have been mainly studied in relation with reading, which is the main complaint of these kind of patients. However, there are not enough data regarding perception of objects and spaces in this population. Then, the objectives are to study the visual-spatial abilities in individuals with vision loss, and altered cognitive processes, (2) to develop clinics tools for early detection and quantification of visual-spatial deficits and (3)to understand the capacities of normal peripheral vision in order to test the possibility of potential training for use of peripheral vision when central vision is impaired by an ophthalmic pathology.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
260
Inclusion Criteria

Not provided

Exclusion Criteria
  • Psychiatric disease or neurological pathologies
  • Communication difficulties (deafness / mutism)
  • Drug treatment altering concentration
  • Mental deterioration with MMS <24
  • Alcoholism or addiction to drugs
  • Persons under guardianship

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Control groupvision testsPatients without loss of vision.
Patients with loss of central visionvision testsPatients coming in ophthalmic consultation will be selected for the study. The diagnosis of this disease is based on clinical examination, and imaging of the retina.Patients with only loss of central vision will be selected.
Patients with loss of peripheral visionvision testsPatients coming in ophthalmic consultation will be selected for the study. Patients with loss of peripheral vision will be selected on the bases of presence of tunnel vision.
Primary Outcome Measures
NameTimeMethod
Comparison of performances in visual tests between different groups according to answer timeat inclusion

These behavioral studies include a series of short tests of 5 to 10 minutes each (not exceeding 60 minutes with breaks and instructions) in which photos of scenes or isolated objects will be presented in central or peripheral vision using a computer screen or a panoramic screen covering a 180° field.

Comparison of performances in visual tests between different groups according to error rateat inclusion

These behavioral studies include a series of short tests of 5 to 10 minutes each (not exceeding 60 minutes with breaks and instructions) in which photos of scenes or isolated objects will be presented in central or peripheral vision using a computer screen or a panoramic screen covering a 180° field.

Secondary Outcome Measures
NameTimeMethod
Pearson correlation coefficient to determine the correlation between the performance parameters during visual tests (error rate and answer time) and clinical parameters (visual acuity and lesion size)at inclusion

These behavioral studies include a series of short tests of 5 to 10 minutes each (not exceeding 60 minutes with breaks and instructions) in which photos of scenes or isolated objects will be presented in central or peripheral vision using a computer screen or a panoramic screen covering a 180° field.

Estimation of the score of visual acuity by the logMAR chartat inclusion
Measure of lesion sizeat inclusion
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