Effect of intravenous Dexamethasone(Drug) on subsyndromal delirium after abdominal surgery in older patients
Not Applicable
- Conditions
- Health Condition 1: Z768- Persons encountering health services in other specified circumstances
- Registration Number
- CTRI/2022/07/043838
- Lead Sponsor
- Dr Vimi Rewari
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Adults >60 years age
2.Undergoing elective abdominal surgery of >60 minutes duration under
GA( gastrointestinal surgery, gynecological surgery, urological surgery, hepatobiliary
surgery)
3.Competent to provide informed consent
Exclusion Criteria
1.Patients who refuse to give consent
2.Patients with preexisting cognitive impairment(Mini mental state examination score <25)
3.Preoperative onset of delirium
4.Patients with uncontrolled diabetes mellitus
5.Visual or hearing disability
6.Drug or alcohol abuse
7.Patients who received any steroid in the last week prior to surgery
8.Patients likely to need intensive care
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method incidence of PSSD in the first three postoperative days using the CAM scoreTimepoint: post-op day 0,1,2 and 3
- Secondary Outcome Measures
Name Time Method 1. using Numeric Rating Scale (NRS) (0-10), pain at rest and on coughing averaged (arithmetic mean) across postop days 1, 2 and 3. <br/ ><br>2. Postoperative cumulative opioid use measured as oral morphine equivalent. <br/ ><br>3. Incidence of Postoperative Delirium (PD) in first three postoperative days. <br/ ><br>4. Incidence of PSSD which progressed to PD. <br/ ><br>5. Identification of risk factors for development of PSSD and PD. <br/ ><br>6. Correlation of pain and opioid use with PSSD and PD. <br/ ><br>7. Length of hospital stay. <br/ ><br>8. 30 day mortality rateTimepoint: post-op day 0,1,2 and 3