ACTRN12612000833864终止4 期
An open-label randomised pilot trial comparing outcomes of oral versus intravenous antibiotic therapy for the treatment of the diabetic foot wound complicated by osteomyelitis
Southern Health0 个研究点目标入组 7 人开始时间: 2012年8月7日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 发起方
- 入组人数
- 7
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •18 years or older; currently treated patient at Southern Health; Diagnosis of Type I or Type II diabetes mellitus; Diabetic foot osteomyelitis confirmed on MRI, Plain X-ray and clinical signs and symptoms; adequate macrovascular blood supply; adequate debridement of infected tissue; known pathogen(s); suitable for oral and intravenous antibiotic therapy; two weeks or less of IV antibiotic therapy for diabetic foot osteomyelitis at baseline.
排除标准
- •Females that are pregnant or breastfeeding; sepsis at presentation; positive blood culture within 14 days of presentation; inadequate macrovascular supply; amputation of infected limb planned/performed; pathogen unknown; known pathogens resistant to appropriate oral and/or IV antibiotics included in treatement strategy; more than 14 days of IV antibiotic therapy prior to baseline; allergy or other absolute contraindication to the oral and/or IV antibiotics listed in treatment strategy; implant or prosthetic device in infected limb; has another condition that requires treatment with antibiotics for greater than one week prior to baseline.
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