Effect of Enhanced Recovery After Surgery (ERAS) on Inflammatory Response After Planned Abdominal Hysterectomy

• Conditions: Hysterectomy

• Registration Number: NCT01747005
• Lead Sponsor: Antypin Eduard Eduardovich

Brief Summary

The aim of study is to determine effect of enhanced recovery after surgery (ERAS) on inflammatory response after abdominal hysterectomy.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-06
• Study First Submitted: 2012-11-27
• Study First Submitted QC: 2012-12-09
• Study First Posted: 2012-12-11
• Status Verified: 2015-11
• Last Update Submitted: 2015-11-16
• Last Update Posted: 2015-11-17
• Primary Completion: 2015-12
• Study Completion: 2015-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

• Informed consent
• Abdominal hysterectomy
• ASA class I or II

Exclusion Criteria

• psychiatric disorders
• ASA III and IV
• Chronic inflammatory disorders
• Pregnancy
• Local anesthetics allergy
• Coagulation disorders
• patients receiving anticoagulants

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change of Serum level of IL-1beta,IL-6,CRP,Cortisol,IL-4 by immuno-ferment analysis.	baseline, 24 hour post-operative and 7 days post-operative

Secondary Outcome Measures

Name	Time	Method
Change of postoperative pain, fatigue and postoperative nausea and vomiting	baseline,6,12,24,48 hour and 7 days postoperatively	Postoperative pain will be assessed by visual analogue scale. Postoperative fatigue will be assessed by modified analogue scale. incidence of postoperative of nausea and vomiting

Trial Locations

Locations (1)

Samoilova maternity home; 🇷🇺 Arkhangelsk, Arkhangelskya oblast, Russian Federation