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临床试验/NCT05236933
NCT05236933已完成不适用

Association Between Types of Pain and Motor Activities Physical Activity in Individuals With Spinal Cord Injury

Temple University1 个研究点 分布在 1 个国家目标入组 17 人开始时间: 2022年3月24日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
17
试验地点
1
主要终点
Change in pain intensity over 1 week

研究概览

简要总结

This study will investigate the relationships between: (1) physical activity (PA) and types of chronic pain (nociceptive and neuropathic), and (2) virtual reality (VR) and types of chronic pain (nociceptive and neuropathic).

详细描述

Chronic pain can be differentiated by its underlying mechanisms. However, this important distinction is not applied to most non-pharmacological treatment approaches. Studies that have shown modulation of chronic pain with physical activity (PA) or virtual reality (VR) have not evaluated differential effects on nociceptive and neuropathic pain. Therefore, it is unknown if neuropathic pain and nociceptive pain respond differently to PA and VR, and if treatment could be optimized through targeted interventions or a combination of interventions. Understanding the relationships between different types of pain and motor activity will provide new insight to inform future recommendations to alter PA levels for pain modulation.

A prospective, cohort design will be employed for this study of individuals with SCI for a duration of one week in the community. This study will identify trends that are different between the responses of different types of pain and motor activities (i.e., PA and VR). The data obtained will also capture fluctuations in PA levels across participants and corresponding pain levels because PA levels will be collected through real-world data in the community.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosis of spinal cord injury (SCI) (at least six months post-SCI)
  • Experienced chronic pain for a duration of at least 6 months
  • Functionally able to self-propel a manual wheelchair
  • Medically stable

排除标准

  • History of motion sickness or epilepsy
  • Condition in which PA is medically contraindicated

结局指标

主要结局

Change in pain intensity over 1 week

时间窗: Measured repeatedly at set intervals; at baseline, 15 minutes after baseline assessment, and once daily for 1 week

Patient-reported rating of pain intensity collected using the International SCI Pain Basic Data Set Version 2.0 (Widerstrom-Noga et al., 2014). This measure provides information regarding the location and severity of pain on a 0-10 scale, where higher number indicates worse pain, and categorization of pain into neuropathic and nociceptive.

次要结局

  • Pain interference(Measured once at baseline)
  • Kinesiophobia(Measured once at baseline)
  • Conditioned pain modulation(Measured once at baseline)
  • Depression(Measured once at baseline)
  • Virtual embodiment(Measured once at baseline)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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