Effects of Dark Chocolate on the Risk Factors of Cardiovascular Diseases
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- Change of systolic and diastolic blood pressure
研究概览
简要总结
Cardiovascular disease (CVD) is the number one cause of death in the US. Epidemiologic evidence supports that antioxidant-rich diets promote health and attenuate or delay the onset of CVD. Cocoa and chocolate products have among the highest antioxidant concentrations compared to other antioxidant food sources. The objective of this study is to examine the effects of regular dark chocolate, bloomed dark chocolate, and white chocolate on cardiovascular health markers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Generally healthy subjects
排除标准
- •Pregnant woman
- •Lactose intolerance
- •Required dietary supplement use
- •Required medication of metabolic disorders
- •Allergy to cacao
研究组 & 干预措施
White chocolate
Subjects consume 50g of white chocolate daily for 15 days.
干预措施: White chocolate (Other)
Dark chocolate
Subjects consume 50g of dark chocolate daily for 15 days.
干预措施: Dark chocolate (Other)
结局指标
主要结局
Change of systolic and diastolic blood pressure
时间窗: Baseline and Day 15
Change of systolic and diastolic blood pressure will be determined to examine effects of dark chocolate consumption vs white chocolate.
Change of skin blood flow level
时间窗: Baseline and Day 15
Change of skin blood flow level will be determined using Laser Doppler Flowmetry to examine effects of dark chocolate consumption vs white chocolate. Laser Doppler flowmetry is an optical technology widely used in research to measure blood flow. It is a non-invasive, painless technique for studying microcirculatory changes in tissue.
Change of HDL cholesterol level
时间窗: Baseline and Day 15
Change of blood cholesterol level will be determined to examine effects of dark chocolate consumption vs white chocolate.
Change of antioxidant levels
时间窗: Baseline and Day 15
Change of antioxidant levels will be determined to examine effects of dark chocolate consumption vs white chocolate.
次要结局
未报告次要终点