Validation Study of the S-1 dosage formula based on renal function (SCHOLAR Study: Part 2)
Not Applicable
- Conditions
- Patients with cancer scheduled to have S-1 monotherapy
- Registration Number
- JPRN-UMIN000023880
- Lead Sponsor
- Keio University School of medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
1) pulmonary fibrosis and interstitial pneumonia 2) diarrhea 3) active infection 4) require blood transfusion within 14 days 5) severe complications 6) dialysis 7) massive abdominal and pleural effusion 8) Being treated with flucytosine. 9) mental disease 10) hypersensitive to 5-FU 11) Any patients judged by the investigator to be unfit to participate in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To confirm AUC of 5-FU was valid when S-1 calculated by B-B formula was administered
- Secondary Outcome Measures
Name Time Method To evaluate safety when S-1 calculated by B-B formula was administered