Comparison of Different Methods of Hyaluronic Acid Application on Skin Parameters
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 23
- 试验地点
- 2
- 主要终点
- Change in skin hydration level
研究概览
简要总结
This study aims to compare the effects of two different methods of applying hyaluronic acid (HA) on skin parameters in healthy individuals. HA is a widely used ingredient in skincare products due to its hydrating properties. However, it is unclear whether applying HA to dry or pre-moistened skin provides better results in terms of skin hydration and texture.
In this non-invasive, interventional trial, 23 healthy volunteers aged 18 to 50 will be randomly assigned to two groups. One group will apply HA to dry skin, while the other will apply HA to moistened skin. Skin parameters will be measured before and after the intervention to assess hydration, transepidermal water loss, and overall skin condition.
The aim is to determine the optimal method of HA application that maximizes its effectiveness in improving skin quality. Participants may benefit from improved skin hydration and increased awareness of the best application method for their skin type. No significant risks are expected from participation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy individuals aged 18 to 50 years
- •Willingness to apply the product daily for 3 weeks
- •Ability to attend all scheduled skin assessments (baseline + weekly)
- •Provided written informed consent
排除标准
- •Known allergy or sensitivity to hyaluronic acid or any component of the product
- •Active skin diseases or dermatological conditions in the facial area
- •Use of systemic or topical corticosteroids or retinoids within 4 weeks prior to study
- •Pregnancy or breastfeeding
- •Participation in another clinical trial within the past 30 days
结局指标
主要结局
Change in skin hydration level
时间窗: Baseline, Week 1, Week 2, Week 3
Skin hydration will be measured at four time points using a corneometer or comparable non-invasive skin analysis device. Measurements will be taken before the intervention (baseline) and at the end of each week to assess cumulative and comparative effects of hyaluronic acid application.
Change in skin hydration level
时间窗: Baseline, Week 1, Week 2, Week 3
Skin hydration will be measured at four time points using a corneometer or comparable non-invasive skin analysis device. Measurements will be taken before the intervention (baseline) and at the end of each week to assess cumulative and comparative effects of hyaluronic acid application.
次要结局
未报告次要终点