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Clinical Trials/NCT05171231
NCT05171231
Completed
Not Applicable

Observational, Multicenter, Prospective Clinical Study, Measuring the Performance and Safety of the Surgical Hemostatic Agent "HEMOCOLLAGENE®" in Patients Requiring Oral Surgery

Septodont8 sites in 2 countries125 target enrollmentNovember 3, 2021
ConditionsOral Hemorrhage

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Oral Hemorrhage
Sponsor
Septodont
Enrollment
125
Locations
8
Primary Endpoint
Hemostatic Performance at 5 minutes
Status
Completed
Last Updated
last year

Overview

Brief Summary

The aim of this study is to collect performance and safety data relating to the use and the follow-up of the HEMOCOLLAGENE® medical device in routine clinical practice from various hospitals and medical centers in oral dental surgery.

Patients will The data collected from the Post-Market Clinical Follow-up study will be used to support the regulatory requirements of post-market monitoring (risk management, residual risks, instructions for use...) and to increase the manufacturer's clinical data. Patients will be followed for 1 month.

Adverse events (safety) and device performance will be collected by the dentist during the routine follow-up visits.

Registry
clinicaltrials.gov
Start Date
November 3, 2021
End Date
March 7, 2022
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Septodont
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient requiring oral surgery
  • Patient with a bleeding requiring the use of an adjuvant hemostatic
  • Patient implanted with HEMOCOLLAGENE® in dental surgery.
  • Patient who signed his informed consent form

Exclusion Criteria

  • Inform Consent not signed
  • Patients with acute oral infection.
  • Patients with an unstable hemodynamic state (acute and/or chronic cardiovascular pathology, low arterial pressure, cardiac rhythm problem)
  • Pregnant and / or breastfeeding patients.
  • Patient with hypersensitivity or allergy to bovine collagen

Outcomes

Primary Outcomes

Hemostatic Performance at 5 minutes

Time Frame: 5 minutes after treatment onset

Evaluation of the stop of the bleeding 5 minutes after using HEMOCOLLAGENE®.

Secondary Outcomes

  • Wound Healing(At 30 days)
  • Rate of persistant bleeding(5 minutes after treatment onset)
  • Ease of the use of Hemocollagene by the Dentist(At day 0, after using the treatment)
  • Rate of device related adverse events(From treatment onset to 30 days)
  • Rate of overall adverse events(From treatment onset to 30 days)
  • Rate of hemostatic time at 10 minutes in case persistant bleeding(10 minutes after treatment onset)

Study Sites (8)

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