Local Recurrence Prediction of by Texture Analysis Derived From Positron Emission Tomography (PET / CT) Imaging of Non-small Cell Lung Cancer (NSCLC) Treated With Stereotactic Radiotherapy (SBRT) (Retros MUMOFRAT)

Completed

• Conditions: Identify FDG PET/CT Parameters Predictive of Local Control

• Registration Number: NCT06555861
• Lead Sponsor: University Hospital, Brest

Brief Summary

The aim of this retrospective multicentric study was to develop and evaluate a prognostic FDG PET/CT radiomics signature in early-stage non-small cell lung cancer (NSCLC) patients treated with stereotactic radiotherapy (SBRT).

Detailed Description

Not available

Study Timeline

• Status Verified: 2018-12
• Study Start: 2019-01-07
• Primary Completion: 2019-02-06
• Study Completion: 2019-02-06
• Study First Submitted: 2024-08-13
• Study First Submitted QC: 2024-08-13
• Last Update Submitted: 2024-08-13
• Study First Posted: 2024-08-15
• Last Update Posted: 2024-08-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 87

Inclusion Criteria

• NSCLC stage I-II treated by SBRT
• PET/CT imaging performed within 60 days of SBRT

Exclusion Criteria

• Lack of follow-up
• Refusal of consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Local Recurrence	Time-to-Event measures up to 5 years	accuracy

Secondary Outcome Measures

Name	Time	Method
Distant metastasis free survival	Time-to-Event measures up to 5 years	accuracy
Overall survival	Time-to-Event measures up to 5 years	accuracy
Cancer specific survival	Time-to-Event measures up to 5 years	accuracy
Recurrence free survival	Time-to-Event measures up to 5 years	accuracy

Trial Locations

Locations (4)

ICO; 🇫🇷 Nantes, Saint Herblain, France

CHRU de Brest; 🇫🇷 Brest, France

Centre Eugènes Marquis; 🇫🇷 Rennes, France

CHU de Tours; 🇫🇷 Tours, France