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Clinical Trials/NCT06090942
NCT06090942
Not yet recruiting
Not Applicable

The Effectiveness of Cognitive Training for Digital Biomarkers: Evidence From the Urban and Rural Area

Taipei Medical University0 sites90 target enrollmentOctober 20, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cognitive Decline
Sponsor
Taipei Medical University
Enrollment
90
Primary Endpoint
digital biomarker
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

This study aims to conduct cognitive training for digital biomarkers among older adults.

Detailed Description

The prevalence of dementia in rural areas is higher than in urban areas. However, the resource and research input on cognitive training for rural older adults still needs improvement. There is also no solution for preventing or early detection of dementia in rural areas. Unlike biomarkers that require invasive detection, digital biomarkers have been advocated in recent years for early disease prediction. However, there are still few studies on the effectiveness of digital biomarkers in evaluating cognitive function in the elderly. In addition, although previous studies have confirmed that cognitive training can be effective for older adults, it is difficult for the elderly in rural areas to obtain these cognitive-promoting resources due to distance. Moreover, the autonomy and right of choice of older adults are the keys to the success of their health behavior change.

Registry
clinicaltrials.gov
Start Date
October 20, 2023
End Date
July 31, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Huie-Ling Chiu

Associate professor

Taipei Medical University

Eligibility Criteria

Inclusion Criteria

  • At least 60 years of age, Can communicate in Chinese (Taiwanese)
  • Bring your own mobile device with Internet access.
  • Can act alone without physical impairment;full score of basic activities of daily living scale and instrumental activities of daily living scale.

Exclusion Criteria

  • Dementia diagnosed by a physician and in compliance with ICD-10
  • Physician diagnosed with significant mental illness or communication impairment
  • Participated in other cognitive training studies within the past year
  • Medical conditions associated with rapid functional and cognitive decline
  • Severe visual impairment

Outcomes

Primary Outcomes

digital biomarker

Time Frame: pretest, immediate post test, 3 month follow-up, 6 month follow-up

wearable device of stress and sleep, EEG power in alpha band, Delta and Theta frequency-bands

Secondary Outcomes

  • Montreal Cognitive Assessment(MoCA)(pretest, immediate post test, 3 month follow-up, 6 month follow-up)
  • Digit Span(DS)(pretest, immediate post test, 3 month follow-up, 6 month follow-up)
  • Digit Vigilance Test(DVT)(pretest, immediate post test, 3 month follow-up, 6 month follow-up)
  • Computerized version of Wisconsin Card Sort Test (WCST)(pretest, immediate post test, 3 month follow-up, 6 month follow-up)
  • Stroop color-word test (SCWT)(pretest, immediate post test, 3 month follow-up, 6 month follow-up)

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