Comparison of efficacy of ultrasound- guided erector spinae plane block versus local wound infiltration for post-operative analgesia in patients undergoing video-assisted thoracoscopic surgery: a double blind randomised controlled trial
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- The time to request the first post-operative rescue analgesic dose
研究概览
简要总结
This study is a randomized, double blind, parallel group, single-centre trial comparing the efficacy of ultrasound-guided erector spinae plane block versus local wound infiltration for post-operative analgesia in patients undergoing video-assisted thoracoscopic surgery in 110 patients in a tertiary care centre in India. The primary outcome measure will be to determine the time to request the first post-operative rescue analgesic dose. The secondary outcomes will be total post-operative rescue analgesic requirement, comparison of quality of recovery, incidence of nausea and vomiting in the first 24 hours post-operatively and numerical rating score at rest and during coughing, comparison of sedation scores at 6, 12, and 24 hours post-operatively
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Informed and written consent ASA physical status 1 and 2 Elective video-assisted thoracoscopic surgery.
排除标准
- •Patient refusal Infection at the site Chronic pain patients or patients with analgesic dependence INR more than 1.5 Difficulty in understanding or non-compliance with the quality of recovery questionnaire.
结局指标
主要结局
The time to request the first post-operative rescue analgesic dose
时间窗: The time point at which the patient requests the first post-operative rescue analgesic dose in first 24 hours.
次要结局
- Total post-operative rescue analgesic requirement(24 Hours post-operatively)
- Numerical rating score at rest and during coughing(6 ,12 and 24 Hours post-operatively)
- Comparison of quality of recovery(24 Hours post-operatively)
- Comparison of sedation scores(6,12, and 24 Hours post-operatively)
- Incidence of nausea and vomitting(Post-operative period for 24 Hours)
研究者
Monika Yadav
Medanta -The Medicity