跳至主要内容
临床试验/NCT02192658
NCT02192658已完成不适用

Disability and HIV: an Appraisal of the Vulnerability of People With Disabilities to HIV Infection in Two Main Cities of Sub-Saharan Africa

ANRS, Emerging Infectious Diseases0 个研究点目标入组 1,610 人开始时间: 2014年11月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
1,610
主要终点
HIV prevalence

研究概览

简要总结

According to the recent World Report on Disability, around 15% of the world population lives with a disability and 80% of people with disabilities (PWD) live in developing countries. More and more evidence show that PWD are more likely to be poor, vulnerable to physical and sexual violence, and to have less access to education. Therefore, PWD are likely to have an increased risk for HIV infection, potentially being a key population in regard to this epidemic.

The vulnerability of PWD was recognized in 2007 by the United Nations Convention on the Rights of Persons with Disabilities. However, data on the extent how PWD are affected by HIV is still very limited. As a result, PWD are usually overlooked by National AIDS Control Programmes and few projects specifically targeting them have been developed.

Recognizing the need for appropriate and reliable data to help protect the rights of PWD and achieve a better inclusion of disability in National AIDS Control Programmes, the Institute of Research for Development (IRD), the Institut de Formation et Recherche Demographique (IFORD) and Handicap International (HI) propose this study that aims to provide quantitative and qualitative data on the vulnerability of PWD to HIV infection in Cameroon and Burkina Faso, in order to define if this vulnerable population is also a Key Population in relation to the HIV epidemic. This study adopts a multidisciplinary approach (quantitative and qualitative methods). Quantitative data are collected only in Cameroon.

Only the quantitative study is described here.

详细描述

OBJECTIVES:

The general objective of this study is to provide information on the vulnerability of PWD to HIV infection.

The objectives of the quantitative component of this study are:

Estimation of the HIV burden among PWD:

  • To estimate the prevalence of HIV in PWD comprehensively and for each of the following disabilities 1) hearing 2) visual 3) mobility 4) cognitive (intellectual)
  • To compare the HIV prevalence between PWD and non-disabled matched controls
  • To assess the association between PWD's social network characteristics and the risk for HIV

研究设计

研究类型
Observational
时间视角
Cross Sectional

入排标准

年龄范围
15 Years 至 49 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Age 15 to 49 years
  • WG criteria: ≥ 1 major impairment or 2 minor difficulties with an activity
  • Informed consent given

排除标准

  • Any severe disease that, according to the investigator, precludes the participation of the subject to ANY aspect of the study
  • Temporary impairment (>1 year) which is likely to be cured quickly
  • Subject consenting to none of the aspects of the study.
  • For Non-Disabled People (control group):
  • Inclusion criteria:
  • Age 15 to 45 years in an interval of 5 years compared to the index PWD;
  • Same sex as the index PWD;
  • Not answering to the WG criteria for disability;
  • Living in the same enumeration area as the Index PWD;
  • Informed consent given.
  • Exclusion criteria:
  • Any conditions, that - according to the interviewer - don't permit to participate at any part of the study;
  • Subject consenting to none of the aspects of the study.

结局指标

主要结局

HIV prevalence

时间窗: 10 months

HIV prevalence among People With Disability compared to Non-Disabled People. HIV serology will be assessed by rapid diagnostic tests.

次要结局

  • Risk factors(10 months)

研究者

申办方类型
Other Gov
责任方
Sponsor

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