FEBCON-ED Study: Does advice to give regular antipyretics for children presenting with a FEBrile CONvulsion to the Emergency Department reduce the rate of seizure reoccurrence within the same febrile illness?
- Conditions
- Febrile ConvulsionsEmergency medicine - Other emergency careNeurological - Other neurological disorders
- Registration Number
- ACTRN12623000638639
- Lead Sponsor
- Prof Simon Craig
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 9600
A child with an ED diagnosis of a febrile convulsion (defined as a seizure occurring in a child without previous afebrile seizures, without significant prior neurological abnormality and without signs of central nervous system infection or metabolic disturbance) who is planned for discharge home after a period of observation from the ED or ED short stay unit.
(a) a child diagnosed with a febrile convulsion who is planned to be admitted to a hospital ward;
(b) a child with an ED length of stay of greater than 18 hours (to allow for shorter periods of and/or overnight observation in a short-stay unit or similar setting);
(c) a child presenting to the ED with an afebrile convulsion;
(d) a child with a history of epilepsy or a history of afebrile seizures;
(e) a child with status epilepticus requiring at least one second-line agent (such as phenytoin or levetiracetam) to terminate their seizures;
(f) a child with a known allergy to both paracetamol or ibuprofen, or a medical condition in which both these medications would be contraindicated.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reoccurrence of febrile convulsion within the same febrile illness - assessed by parent/guardian report (via outcome survey) and verified by medical record review (composite primary outcome).<br>[ - 3 and 7 days after ED presentation with febrile convulsion - parent/guardian survey<br> - 7 days after ED presentation with febrile convulsion - medical record review]
- Secondary Outcome Measures
Name Time Method