Comparison of Aqueous and Plasma Glucose Level in Diabetic Patients
Not Applicable
- Conditions
- Diabetes Mellitus
- Interventions
- Other: Glucose measurement
- Registration Number
- NCT02750098
- Lead Sponsor
- Sheba Medical Center
- Brief Summary
Comparison of aqueous and plasma glucose level in diabetic patients
High glucose concentrations in aqueous humor are thought to be related of diabetic ocular injury, including cataract and diabetic keratopathy. The primary mechanisms are nonenzymatic glycation, oxidative stress and activation of polyol pathway. However, glucose concentrations in aqueous humor of diabetic patients was only examined in a few patients in the past.
This study will compare glucose concentration in blood plasma and aqueous humor in diabetic patients undergoing cataract surgery. Perioperative Hemoglobin A1c concentrations will also be examined. Correlation between these parameters will be analyzed.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
- Diabetic patients planed for elective cataract surgery
Exclusion Criteria
- s/p traumatic eye injury
- past or current uveitis
- patients using prescription eye drops except lubricants
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Diabetic patients Glucose measurement Diabetic patients planned to undergo elective cataract surgery
- Primary Outcome Measures
Name Time Method Aqueous humor glucose concentration Day of cataract surgery
- Secondary Outcome Measures
Name Time Method Hemoglobin A1c Perioperative month Plasma glucose concentrations Day of cataract surgery