The effect of eplerenone on ischemia reperfusion injury in human myocardium

Completed

• Conditions: ischemia reperfusion injury; myocardial infarction; 10011082

• Registration Number: NL-OMON40313
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

- age >18 years
- cardiac surgery with extracorporeal circulation

Exclusion Criteria

* Use of theophylline
* Use of sulfonylureas
* Use of oral antiarrhythmics ( not betablockers)
* Atrial arrhythmias
* Right ventricular failure
* Known atrial enlargement

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The effect of eplerenone of the recovery of contractile function after<br /><br>simulated ischemia and reperfusion</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>none</p><br>