Long-term Outcomes After Treatment for Superficial Esophageal Squamous Cell Carcinoma
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Esophageal Neoplasms
- Sponsor
- Shanghai Zhongshan Hospital
- Enrollment
- 1800
- Locations
- 1
- Primary Endpoint
- Overall survival
- Last Updated
- 9 years ago
Overview
Brief Summary
Tumor is the primary public health problem and the incidence of esophageal cancer showed the increasing trend in the past thirty years. According to the statistics in 2015, the new onset of esophageal cancer is about 477,900 yearly. The mainly pathologic type of esophageal cancer in China is esophageal squamous cell carcinomas, which accounts for more than 90% of patients in China. With the development of endoscopic technics, more and more patients choose to receive the endoscopic procedure rather than traditional surgery. However, the long-term efficacy and outcomes of patients with superficial esophageal squamous cell carcinoma received different interventions remained unclear. Thus, investigators aim to conduct a multi-center retrospective study to investigate the long term outcomes of superficial esophageal squamous cell carcinoma patients receiving endoscopic treatment and surgery.
Investigators
Shiyao Chen
Professor
Shanghai Zhongshan Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients received endoscopic treatment because of the superficial esophageal disease and had the pathologic diagnosis of squamous cell carcinoma.
Exclusion Criteria
- •Combined with other severe disease
- •With a history of esophageal surgery
- •Combined with other malignant disease
Outcomes
Primary Outcomes
Overall survival
Time Frame: 3 years after treatment
Secondary Outcomes
- Long-term complications incidence rate(3 years after treatment)
- Recurrence rate(3 years after treatment)
- Short-term complications incidence rate(30 days after treatment)