Long-term Outcomes After Treatment for Superficial Esophageal Squamous Cell Carcinoma
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,800
- 试验地点
- 1
- 主要终点
- Overall survival
研究概览
简要总结
Tumor is the primary public health problem and the incidence of esophageal cancer showed the increasing trend in the past thirty years. According to the statistics in 2015, the new onset of esophageal cancer is about 477,900 yearly. The mainly pathologic type of esophageal cancer in China is esophageal squamous cell carcinomas, which accounts for more than 90% of patients in China. With the development of endoscopic technics, more and more patients choose to receive the endoscopic procedure rather than traditional surgery. However, the long-term efficacy and outcomes of patients with superficial esophageal squamous cell carcinoma received different interventions remained unclear. Thus, investigators aim to conduct a multi-center retrospective study to investigate the long term outcomes of superficial esophageal squamous cell carcinoma patients receiving endoscopic treatment and surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients received endoscopic treatment because of the superficial esophageal disease and had the pathologic diagnosis of squamous cell carcinoma.
排除标准
- •Combined with other severe disease
- •With a history of esophageal surgery
- •Combined with other malignant disease
结局指标
主要结局
Overall survival
时间窗: 3 years after treatment
次要结局
- Long-term complications incidence rate(3 years after treatment)
- Recurrence rate(3 years after treatment)
- Short-term complications incidence rate(30 days after treatment)
研究者
Shiyao Chen
Professor
Shanghai Zhongshan Hospital