ISRCTN91548930已完成2 期
A single arm, multi-centre, two stage, phase II study of imatinib in good performance status patients with c-kit positive metastatic melanoma
Clatterbridge Centre for Oncology NHS Foundation Trust (UK)0 个研究点目标入组 25 人开始时间: 2008年2月13日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 25
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Patients with histologically or cytologically confirmed unresectable, metastatic uveal melanoma (c-kit positive on immunohistochemistry [IHC])
- •2. Any prior therapy for advanced disease excluding agents targeting c-kit
- •3. Life expectancy greater than 12 weeks
- •4. World Health Organization (WHO) performance status 0, 1 or 2
- •5. Presence of one or more measurable lesions
- •6. Age greater than 18 years, either sex
- •7. Adequate haematological, renal and liver function
- •8. Written informed consent provided by the patient
排除标准
- •1. C-kit negative uveal melanoma
- •2. Any previous investigational agent within the last 12 weeks
- •3. Known leptomeningeal or brain metastases
- •4. Any other serious or uncontrolled illness which, in the opinion of the investigator, makes it undesirable for the patient to enter the trial
- •5. Any medical or psychiatric condition which would influence the ability to provide informed consent
- •6. Pregnant or lactating women
研究者
相似试验
进行中（未招募）
1 期
A clinical trial investigating the use of BTT1023 in patients with PSCPrimary Sclerosing Cholangitis (PSC)MedDRA version: 20.1Level: LLTClassification code 10036732Term: Primary sclerosing cholangitisSystem Organ Class: 100000004871EUCTR2014-002393-37-GBniversity of Birmingham23
进行中（未招募）
1 期
A single arm, multicenter, single-stage phase II trial of RAD001 in Advanced and Metastatic Silent neuro-Endocrine Tumours in Europe - RAMSETEEUCTR2008-006182-88-DEovartis Pharma Services AG69
进行中（未招募）
不适用
A single arm, multicenter, single-stage phase II trial of RAD001 in Advanced and Metastatic Silent neuro-Endocrine Tumours in Europe - RAMSETEEUCTR2008-006182-88-NLovartis Pharma Services AG69
进行中（未招募）
1 期
A single arm, multicenter, single-stage phase II trial of RAD001 in Advanced and Metastatic Silent neuro-Endocrine Tumours in EuropeEUCTR2008-006182-88-SEovartis Pharma Services AG69
进行中（未招募）
1 期
A single arm, multicenter, single-stage phase II trial of RAD001 in Advanced and Metastatic Silent neuro-Endocrine Tumours in EuropeEUCTR2008-006182-88-GBovartis Pharma Services AG73