Evaluation of Smartphone-based Monitoring as a Biomarker of Deep-brain Stimulation Response in Parkinson’s disease
- Conditions
- G20.90
- Registration Number
- DRKS00025816
- Lead Sponsor
- niversitätsklinikum Düsseldorf
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Levodopa treatment for at least 3 months prior to the first measurement
- Ability to understand the study procedure
- Planned THS surgery for the treatment of idiopathic Parkinson's syndrome
- Eligible for MRI measurement
- Informed consent, signed and dated by the subject or, in the case of motor impairment, by an independent witness
- Presence of a legally authorized representative
- Presence of conditions other than idiopathic Parkinson's disease that may worsen motor or cognitive abilities, such as corticobasal syndrome, multisystem atrophy, dementia, severe arthritis, drug/alcohol abuse, Alzheimer's disease, stroke, or similar conditions
- Inability to remain seated in the MEG scanner without involuntary movements producing artifacts
- Inability to undergo MRI scanning, e.g., metal implants or tattoos containing metal
- Past or present participation in pharmacologic clinical trials related to idiopathic Parkinson's syndrome
- Claustrophobia
- Unable to tolerate levodopa medication withdrawal for at least 12 hours (including dysphagia, tendency to fall)
- Inability to walk
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method