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The evaluation of the Effect of Fingolimod on Fatigue and depression in patients with M.S

Not Applicable
Conditions
multiple sclerosis.
multiple sclerosis
Registration Number
IRCT201407018323N11
Lead Sponsor
Deputy of Research and Technology of Kermanshah University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
40
Inclusion Criteria

Inclusion Criteria: age 18-50 years; definite M.S confirmed by neurologist with relapsing remitting type; disease must be in remission; at least one month after corticostroid therapy; follow up shouldbe possible and patients must be reachable. exclusion criteria: any underlying pulmonary,hepatic,renal or orthopedic; EDSS score>5.5; during follow up events that affect depression happen to the patients.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Fatigue severity. Timepoint: before intervention,3 months after initiation of intervention,6 months after initiation of intervention. Method of measurement: fatigue severity scale.;Degree of depression. Timepoint: before intervention,3 months after initiation of intervention,6 months after initiation of intervention. Method of measurement: beck standard questionare.
Secondary Outcome Measures
NameTimeMethod
iver enzymes concentrations. Timepoint: Before initiation of study,every month for the first 3 months,then every 3 months so on. Method of measurement: Liver function test.;Lymphositic count. Timepoint: Before initiation of study,every month for the first 3 months,then every 3 months after. Method of measurement: CBD-diff.
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