CTRI/2020/08/027364已完成3 期
A multicentric, randomized, double blind, parallel, comparative study to demonstrate the non-inferiority of fixed-dose combination of Efonidipine 40 mg and Chlorthalidone 12.5 mg tablets to fixed-dose combination of Cilnidipine 10 mg and Chlorthalidone 12.5 mg tablets in the management of hypertension.
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 240
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Patients aged ââ?°Â¥18 years.
- •2. Patients diagnosed with Stage-I hypertension (SBP/DBP: 140-159/90-99 mmHg) or Stage-II hypertension (SBP/DBP: ââ?°Â¥160/100 mmHg).
- •3. Patients able to switch all prior antihypertensive medications safely to study medication (Investigatorââ?¬•s discretion).
- •4. Patients willing to sign informed consent.
排除标准
- •1. Patients with known hypersensitivity to diuretics or dihydropyridine calcium channel blockers.
- •2. Patients with history of severe, malignant or secondary hypertension.
- •3. Patient with cerebrovascular disease in the previous 3 months.
- •4. Patients with chronic arrhythmia, sick sinus syndrome or sinus bradycardia ( < 50 beats/min).
- •5. Patients with second- or third-degree atrioventricular block.
- •6. Women who are pregnant, lactating
研究者
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