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临床试验/NCT06549569
NCT06549569已完成不适用

Tilapia Fish Skin Coverage in Acute Thermal Burn; Experimental and Histopathological Study

Aswan University1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2022年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
20
试验地点
1
主要终点
Tilapia Fish Skin Coverage in Acute Thermal Burn

研究概览

简要总结

The goal of this experimental study is to compare TFS and regular dressings as coverage for acute thermal burns. The main question it aims to answer is:

Is TFS effective in treating thermal burns? burn induction was done on rabbits to obtain second-degree thermal burn, followed by coverage with TFS

详细描述

Nile Tilapia Fish Skin (NTFS) has been suggested as an option for biological material for the management of burns. Nile Tilapia Fish Skin also presented a large composition of type I collagen, morphology similar to human skin and high resistance and tensile extension at the break. We chose Baladi rabbits for their relatively ease of handling, accommodation and resistance to surgical aggressions and infectious processes, with low mortality. However, the choice of male rabbits is due to variations in hormonal cycles in females that could intervene in the process of tissue repair.

This experimental model was established to evaluate healing process and outcome results after application of Tilapia Fish Skin on acute contact thermal that was done in order to obtain injuries with the same size and depth.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
1 Year 至 18 Months(Child)
性别
Male
接受健康志愿者

入选标准

  • healthy male one year old rabbit

排除标准

  • female unhealthy rabbits

结局指标

主要结局

Tilapia Fish Skin Coverage in Acute Thermal Burn

时间窗: 1 year

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Amira Anter

resident

Aswan University

研究点 (1)

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